Home

CSF enriched genes in lymphoid and myeloid cells

Figure 2

• A ) Principal component analysis of bulk RNA sequencing of CSF-derived cells and PBMCs. View code.
• B ) Euclidean distance analysis of bulk RNA sequencing of CSF and peripheral blood lymphoid and myeloid cells. View code.
• C ) Volcano plot of differentially expressed genes in myeloid cells between CSF and peripheral blood. Check it closer!
• D ) Volcano plot of differentially expressed genes in lymphoid cells between CSF and peripheral blood. Check it closer!
  View code.
• E ) ID1 and AM2 enriched in myeloid cells in the peripheral blood (left) and CSF (right).
• F ) GNLY and PROKR2 enriched in lymphoid cells in the peripheral blood (left) and CSF (right). View code for E and F.
• G ) Deconvolution analysis with the R package Granulator of the bulk RNA sequencing lymphoid and myeloid cells from both CSF or peripheral blood. View code.
• H ) Deconvolution analysis of the bulk myeloid cell samples using the myeloid cell subclusters from single-cell RNA sequencing data. View code.

n= 6 paired CSF and PBMC samples of bulk sequenced myeloid and lymphoid cells.